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The BISQUE (Bio-Image Semantic Query User Environment) Database, developed at the Center for Bio-Image Informatics at UCSB, was developed for the exchange and exploration of biological images. The Bisque system supports several areas useful for imaging researchers from image capture to image analysis and querying. The bisque system is centered around a database of images and metadata. Search and comparison of datasets by image data and content is supported. Novel semantic analyses are integrated into the system allowing high level semantic queries and comparison of image content.

Bisque integrates with Bio-Formats by calling the showinf command line tool.